RhesusBase News

  1. [2017-10-12] Molecular Biology and Evolution: Isoform Evolution in Primates through Independent Combination of Alternative RNA Processing

  2. [2016-03-21] RhesusBase PopGateway was featured by Molecular Biology and Evolution

    RhesusBase Population Genetics Gateway, an interface to access comprehensive population genetics parameters for each gene in rhesus macaque was featured by Molecular Biology and Evolution. Full text are available:

    Joseph Caspermeyer. First Genome-Wide Mutational Map of Macaques a Boon for Evolutionary Studies. Molecular Biology and Evolution. (2016) doi:10.1093/molbev/msw029. March 21, 2016.

  3. [2016-03-01] Molecular Biology and Evolution: The RhesusBase team release the population genetcis atlas in Rhesus Macaque

  4. [2015-09-03] The RhesusBase team reports the crosstalk between RNA editing regulation and piRNA biogenesis

  5. [2015-08-31] The RhesusBase team reports a new mechanism for the origination of functional human-specific proteins

  6. [2015-06-28] Population Genetics Gateway released!

    RhesusBase PopGateway, the first genome-wide effort to identify and visualize the population genetics profile in rhesus monkey would help the primate research community to clarify the fundamental questions in human biology, underscore functional genes and regulatory regions in the primate evolution, and accelerate the pace of the human translational study.

  7. [2014-04-10] PLOS Genetics: The RhesusBase team release the RNA editome in Rhesus Macaque

  8. [2014-02-27] Molecular Evolution Gateway is published on Molecular Biology and Evolution as Cover Story

  9. [2013-12-11] The ABrowse-mode Genome Browser is updated with UCSC-mode Genome Browser

    A new UCSC-mode Genome Browser is implemented to take place of the previous ABrowser. For ABrowser users, please refer to the URL for the old genome browser, as well as the associated manual, while we highly recommend all RhesusBase users to the newly-implemented, UCSC-mode Genome Browser.

  10. [2013-10-27] Molecular Evolution Gateway released!

    An NGS-oriented genomic framework, the Molecular Evolution Gateway, was developed to access and visualize macaque annotations in reference to human orthologous genes and the associated regulations.

  11. [2013-05-31] RhesusBase releases a user-friendly interface -- UCSC-mode Browser

    The newly-added UCSC-mode genome browser, provides powerful platforms for biologists to fully take advantage of NGS datasets in primates, with tons of canonically-compiled NGS annotations at fingertips without the needs to handle the rawdata with special bioinformatics expertise and computational-intensive effort.

  12. [2013-05-25] Thousands of Next-generation Sequencing datasets were integrated

    Following the rapid pace of Next Generation Sequencing (NGS) technologies, RhesusBase has integrated 1,678 NGS datasets and added 69.5 million new functional annotation records. With one order of magnitude more NGS data, we re-evaluated the previously refined macaque gene models in RhesusBase and assigned RhesusBase quality score to each NGS data. Most exon-intron boundaries were convincingly-revised and 1,200 transcripts with previously extended 3’-UTRs were re-assigned as new splicing isoforms from alternative cleavage and polyadenylation. Overall, RhesusBase will still integrate NGS data of rhesus macaques, and be updated regularly.

  13. [2012-11-29] RhesusBase BioMart joins in BioMart Community

    RhesusBase is a new member of BioMart Community and be available on BioMart Central Portal. RhesusBase BioMart is developed on the basis of BioMart 0.8 framework to customize and facilitate data download, which offers convenient manner to facilitate the offline use of RhesusBase annotations. All annotations and database schemas in RhesusBase are freely accessible by this data portal.

  14. [2012-09-13] RhesusBase RNA-seq data integration

    RhesusBase integrates multi-sample RNA-Seq data of rhesus macaques and provides well-annotated genomic contexts for comparative genomic research. Based on RhesusBase, we performed a comparative transcriptome study in human, chimpanzee, and rhesus macaque, and found that most of the hominoid-specific de novo protein-coding genes encoded long non-coding RNAs (in rhesus macaque). Our results were published on PLoS Genetics on September 13, 2012, and open full text is available:

    Xie C, et al.Hominoid-Specific De Novo Protein-Coding Genes Originating from Long Non-Coding RNAs. PLoS Genetics (2012) doi:10.1371/journal.pgen.1002942

  15. [2012-09-10] RhesusBase 1.0 paper is published on Nucleic Acids Res.

    RhesusBase 1.0 manuscript was sent to Nucleic Acids Research (NAR) on July 9, 2012 and accepted on August 9, 2012. Online publication is available in NAR 2013 Database Issue on September 10, 2012. Abstract and open full text are available:

    Zhang SJ, et al. RhesusBase: a knowledgebase for the monkey research community. Nucleic Acids Res. (2013) doi: 10.1093/nar/gks835. Epub 2012 Sep 10.