For each macaque gene, we provided a Gene Page here to illustrate detailed functional annotations in different categories, such as gene information, expression profile, regulation, variation and repeats, phenotypes and disease, function, as well as drug development.

Summary
Entrez ID: 706009 (Human: 3643)
Offical Symbol: INSR (Human: INSR)
Strand: -
Location: chr19:6981913-7163273
Gene Biotype: protein-coding
Full Name: insulin receptor
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Alias: N.A.
RefSeq: (NW_001106399.1, XM_001094337.2, XP_001094337.2) (NC_007876.1, XM_001094337.2, XP_001094337.2)
Ensembl: (ENSMMUG00000028907, ENSMMUT00000038830, ENSMMUP00000031912) (ENSMMUG00000028907, ENSMMUT00000005264, ENSMMUP00000004959)
UniGene: Mmu.25673
UniProt: N.A.
Publications: N.A.
Wiki: Wikipedia, WikiGenes, GeneCard
RefSeq Summary:

After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]. Refer to NM_000208.
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Structure
RefSeq
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RNA(1)
>gi|297275954|ref|XM_001094337.2| PREDICTED: Macaca mulatta insulin receptor (INSR), mRNA3810nt Get Sequence
[+]
Protein(1)
>gi|297275955|ref|XP_001094337.2| PREDICTED: insulin receptor [Macaca mulatta]1269AA Get Sequence
[+]
Ensembl
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RNA(2)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT000000052642358nt
[+]
>ENSMMUT000000388301122nt
[+]
RhesusBase2 Gene
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RNA(2)
Regions revised by RhesusBase (v2.0) are highlighted in red.
>ENSMMUT000000052642358nt
[+]
>ENSMMUT00000038830.1; Revisions: 3'UTR (chr19:6981549-6981913)1486nt
[+]
Expression
RNA-seq
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RPKM
Reference RNA: 
IMMRT10011037116 (chr19:6977826-6990983, 5252bps)
View:
Lab: 
Burge Charles Gilad2010 Gilad2011 JD Kaessmann Norgren Philipp RB Soojin Wang Yi
Sample: 
brain caudate nucleus cerebellum colon fat frontal cerebral cortex frontal pole heart
hippocampus kidney liver lung lymphoblastoid muscle orbital cerebral cortex spleen
testis thymus
RhesusBase IDLabIndividualSampleRPKM?RPKM Level Housekeeping GenesRB Score?More
RBNGS0120012 Burge B kidney 47.82 (97.16)
694.13 (99.93) Full [+] 7.59 (85.05) [+]
RBNGS0120021 Burge C kidney 34.53 (96.52)
208.26 (99.76) Full [+] 6.88 (70.1) [+]
RBNGS0120003 Burge A kidney 34.07 (95.7)
522.74 (99.88) Full [+] 5.97 (40.72) [+]
RBNGS0120023 Burge C lung 19.23 (91.92)
132.98 (99.35) Full [+] 7.14 (77.84) [+]
RBNGS0120015 Burge B muscle 18.63 (95.4)
869.75 (99.94) Full [+] 6.18 (45.88) [+]
RBNGS0120020 Burge C heart 18.51 (95.26)
559.13 (99.91) Full [+] 5.48 (20.62) [+]
RBNGS0120002 Burge A heart 17.53 (95.2)
814.11 (99.94) Full [+] 5.48 (20.62) [+]
RBNGS0120014 Burge B lung 17.41 (91.98)
169.19 (99.56) Full [+] 7.58 (84.02) [+]
RBNGS0120013 Burge B liver 15.28 (93.81)
370.40 (99.71) Full [+] 7.78 (90.21) [+]
RBNGS0120005 Burge A lung 12.78 (88.84)
85.86 (99.12) Full [+] 6.92 (71.65) [+]
RBNGS0120022 Burge C liver 11.47 (91.42)
252.91 (99.55) Full [+] 7.1 (76.8) [+]
RBNGS0120009 Burge B brain 8.64 (84.4)
593.73 (99.98) Full [+] 7.66 (88.14) [+]
RBNGS0120018 Burge C brain 7.97 (84.54)
601.19 (99.99) Full [+] 6.36 (52.06) [+]
RBNGS0120004 Burge A liver 7.75 (86.82)
367.17 (99.72) Full [+] 7.07 (75.77) [+]
RBNGS0120000 Burge A brain 7.72 (84.22)
552.62 (99.98) Full [+] 6.68 (60.31) [+]
RBNGS0120024 Burge C muscle 7.05 (88.51)
3166.11 (99.96) Full [+] 6.78 (64.43) [+]
RBNGS0120010 Burge B colon 6.54 (79.83)
433.31 (99.85) Full [+] 7.65 (86.6) [+]
RBNGS0120011 Burge B heart 6.46 (87.62)
7151.00 (99.98) Full [+] 7.65 (86.6) [+]
RBNGS0120001 Burge A colon 5.60 (78.02)
426.94 (99.88) Full [+] 6.59 (57.22) [+]
RBNGS0120019 Burge C colon 4.34 (74.06)
546.43 (99.88) Full [+] 7.01 (74.74) [+]
RBNGS0120025 Burge C spleen 4.11 (73.2)
134.12 (99.41) Full [+] 6.95 (73.71) [+]
RBNGS0120016 Burge B spleen 3.98 (73.04)
243.82 (99.72) Full [+] 7.32 (82.99) [+]
RBNGS0120007 Burge A spleen 3.60 (71.64)
152.34 (99.53) Full [+] 6.81 (65.98) [+]
RBNGS0120008 Burge A testis 3.25 (68.69)
237.29 (99.55) Full [+] 7.23 (80.93) [+]
RBNGS0120006 Burge A muscle 2.84 (85.11)
10528.36 (99.98) Full [+] 6.54 (54.12) [+]
RBNGS0120026 Burge C testis 2.58 (63.2)
123.59 (99.40) Full [+] 7.16 (78.87) [+]
RBNGS0120017 Burge B testis 1.67 (61.45)
105.21 (99.15) Full [+] 7.69 (89.18) [+]
RBNGS0120027 Charles 150-99 lymphoblastoid 0.92 (61.81)
3590.65 (99.99) Full [+] 5.9 (37.63) [+]
RBNGS0120030 Charles 256-95 lymphoblastoid 0.29 (56.3)
3288.60 (99.98) Full [+] 5.81 (32.47) [+]
RBNGS0120031 Charles 265-95 lymphoblastoid 0.07 (50.77)
4220.63 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120032 Charles 303-97 lymphoblastoid 0.07 (50.11)
3680.10 (100.00) Full [+] 5.92 (38.66) [+]
RBNGS0120028 Charles 153-99 lymphoblastoid 0.04 (51.34)
4927.60 (100.00) Full [+] 5.83 (35.05) [+]
RBNGS0120029 Charles 173-02 lymphoblastoid 0.02 (47.3)
3034.59 (99.99) Full [+] 5.81 (32.47) [+]
RBNGS0120036 Gilad2010 male1 liver 15.83 (92.2)
284.57 (99.59) Full [+] 5.74 (29.38) [+]
RBNGS0120034 Gilad2010 female2 liver 14.24 (91.38)
265.16 (99.54) Full [+] 5.58 (22.16) [+]
RBNGS0120033 Gilad2010 female1 liver 14.09 (90.99)
246.59 (99.52) Full [+] 5.67 (24.23) [+]
RBNGS0120035 Gilad2010 female3 liver 13.38 (89.19)
509.01 (99.75) Full [+] 5.71 (26.8) [+]
RBNGS0120038 Gilad2010 male3 liver 9.62 (86.29)
295.78 (99.68) Full [+] 5.77 (30.41) [+]
RBNGS0120037 Gilad2010 male2 liver 6.43 (85.29)
342.77 (99.68) Full [+] 5.13 (15.98) [+]
RBNGS0120039 Gilad2011 RNA R1 lymphoblastoid 0.33 (57.79)
2783.10 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120040 Gilad2011 RNA R2 lymphoblastoid 0.08 (51.63)
2909.34 (99.96) Full [+] 5.97 (40.72) [+]
RBNGS0120041 Gilad2011 RNA R3 lymphoblastoid 0.02 (48.4)
2868.12 (99.99) Full [+] 5.98 (43.3) [+]
RBNGS0120042 JD mixtured frontal cerebral cortex 5.89 (71.64)
997.88 (99.99) Full [+] 6.08 (44.85) [+]
RBNGS0120051 Kaessmann male1 kidney 24.80 (94.86)
711.25 (99.96) Full [+] 4.07 (13.92) [+]
RBNGS0120046 Kaessmann female kidney 22.49 (91.64)
1081.82 (99.97) Full [+] 5.72 (28.35) [+]
RBNGS0120045 Kaessmann female heart 12.68 (91.07)
764.28 (99.91) Full [+] 5.25 (18.04) [+]
RBNGS0120050 Kaessmann male1 heart 10.61 (85.72)
599.06 (99.87) Full [+] 5.32 (19.07) [+]
RBNGS0120049 Kaessmann male1 cerebellum 9.80 (81.99)
647.87 (99.97) Full [+] 5.71 (26.8) [+]
RBNGS0120044 Kaessmann female cerebellum 9.39 (82.4)
544.80 (99.97) Full [+] 5.61 (23.2) [+]
RBNGS0120054 Kaessmann male2 brain 7.84 (79.15)
798.21 (99.99) Full [+] 5.23 (17.01) [+]
RBNGS0120047 Kaessmann female liver 7.45 (85.31)
600.89 (99.75) Full [+] 6.19 (46.91) [+]
RBNGS0120048 Kaessmann male1 brain 7.02 (76.22)
1215.60 (99.99) Full [+] 7.17 (79.9) [+]
RBNGS0120043 Kaessmann female brain 6.47 (75.67)
1041.37 (99.99) Full [+] 5.88 (36.6) [+]
RBNGS0120052 Kaessmann male1 liver 5.92 (82.63)
1067.66 (99.83) Full [+] 6.77 (63.4) [+]
RBNGS0120053 Kaessmann male1 testis 1.71 (57.8)
79.24 (97.96) Full [+] 5.81 (32.47) [+]
RBNGS0120055 Kaessmann male2 testis 0.95 (54.35)
73.01 (97.21) Full [+] 7.29 (81.96) [+]
RBNGS0120058 Norgren 001T NHP testis 13.88 (82.69)
361.93 (99.82) Full [+] 6.63 (58.76) [+]
RBNGS0120057 Norgren 001T NHP orbital cerebral cortex 13.05 (82.52)
465.11 (99.89) Full [+] 6.72 (61.34) [+]
RBNGS0120066 Norgren BF23773 frontal cerebral cortex 9.97 (80.81)
780.30 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120065 Norgren BF23764 frontal cerebral cortex 9.88 (80.42)
639.64 (99.96) Full [+] 6.32 (50.0) [+]
RBNGS0120062 Norgren BF21178 frontal cerebral cortex 8.90 (79.26)
975.49 (99.99) Full [+] 6.81 (65.98) [+]
RBNGS0120061 Norgren BF20336 frontal cerebral cortex 8.71 (78.89)
893.81 (99.99) Full [+] 6.85 (68.56) [+]
RBNGS0120064 Norgren BF23762 frontal cerebral cortex 8.62 (78.74)
703.56 (99.97) Full [+] 6.35 (51.03) [+]
RBNGS0120060 Norgren 002T NHP caudate nucleus 7.98 (78.52)
913.62 (99.97) Full [+] 6.93 (72.68) [+]
RBNGS0120056 Norgren 001T NHP caudate nucleus 6.23 (75.9)
634.09 (99.93) Full [+] 6.83 (67.53) [+]
RBNGS0120063 Norgren BF22215 frontal cerebral cortex 5.35 (73.47)
888.73 (99.97) Full [+] 6.63 (58.76) [+]
RBNGS0120059 Norgren 001T NHP thymus 3.91 (71.38)
898.83 (99.94) Full [+] 6.88 (70.1) [+]
RBNGS0120067 Philipp individual brain 0.97 (61.2)
126.37 (99.90) Full [+] 2.33 (9.79) [+]
RBNGS0120070 RB 0605151 fat 29.49 (95.87)
208.39 (99.62) Full [+] 8.59 (94.85) [+]
RBNGS0120072 RB 0605151 kidney 26.10 (95.9)
574.03 (99.91) Full [+] 7.86 (91.75) [+]
RBNGS0120074 RB 0605151 lung 22.63 (94.15)
256.42 (99.77) Full [+] 8.67 (97.42) [+]
RBNGS0120073 RB 0605151 liver 11.28 (90.5)
412.47 (99.69) Full [+] 8.75 (98.45) [+]
RBNGS0120071 RB 0605151 heart 10.54 (93.4)
654.26 (99.90) Full [+] 6.75 (62.37) [+]
RBNGS0120075 RB 0605151 muscle 8.83 (88.1)
4525.95 (99.98) Full [+] 8.76 (99.48) [+]
RBNGS0120069 RB 0605151 cerebellum 7.46 (85.11)
705.06 (99.99) Full [+] 7.86 (91.75) [+]
RBNGS0120068 RB 0605151 brain 5.82 (80.19)
910.13 (99.99) Full [+] 8.23 (93.3) [+]
RBNGS0120077 RB 0605151 testis 4.34 (69.65)
267.33 (99.88) Full [+] 8.59 (94.85) [+]
RBNGS0120076 RB 0605151 spleen 3.90 (69.45)
255.19 (99.72) Full [+] 8.62 (96.39) [+]
RBNGS0120082 Soojin Y04-05 frontal pole 2.59 (94.34)
0.00 (45.92) Full [+] 3.36 (12.89) [+]
RBNGS0120079 Soojin Y04-03 frontal pole 0.10 (63.61)
0.00 (31.36) Full [+] 2.45 (10.82) [+]
RBNGS0120088 Soojin Y04-21 frontal pole 0.09 (62.93)
0.00 (31.03) Full [+] 2.5 (11.86) [+]
RBNGS0120078 Soojin Y04-03 caudate nucleus 0.00 (49.34)
0.00 (49.34) Full [+] 1.77 (2.58) [+]
RBNGS0120080 Soojin Y04-03 hippocampus 0.00 (49.36)
0.00 (49.36) Full [+] 1.88 (5.67) [+]
RBNGS0120081 Soojin Y04-05 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.68 (1.55) [+]
RBNGS0120083 Soojin Y04-05 hippocampus 0.00 (49.5)
0.00 (49.50) Full [+] 1.9 (6.7) [+]
RBNGS0120084 Soojin Y04-20 caudate nucleus 0.00 (49.92)
0.00 (49.92) Full [+] 1.54 (0.52) [+]
RBNGS0120085 Soojin Y04-20 frontal pole 0.00 (49.78)
0.00 (49.78) Full [+] 2.1 (8.76) [+]
RBNGS0120086 Soojin Y04-20 hippocampus 0.00 (49.74)
0.00 (49.74) Full [+] 1.94 (7.73) [+]
RBNGS0120087 Soojin Y04-21 caudate nucleus 0.00 (49.4)
0.00 (49.40) Full [+] 1.81 (3.61) [+]
RBNGS0120089 Soojin Y04-21 hippocampus 0.00 (49.46)
0.00 (49.46) Full [+] 1.84 (4.64) [+]
RBNGS0120092 Wang individual kidney 37.22 (94.29)
1393.19 (99.97) Full [+] 6.2 (47.94) [+]
RBNGS0120091 Wang individual heart 12.92 (91.68)
912.82 (99.92) Full [+] 4.78 (14.95) [+]
RBNGS0120093 Wang individual liver 11.33 (90.3)
338.16 (99.64) Full [+] 5.98 (43.3) [+]
RBNGS0120090 Wang individual brain 7.00 (75.88)
917.80 (99.99) Full [+] 6.28 (48.97) [+]
RBNGS0120094 Wang individual muscle 5.48 (82.8)
5119.89 (99.98) Full [+] 6.58 (55.67) [+]
RBNGS0120095 Wang individual testis 2.24 (60.02)
118.24 (98.89) Full [+] 6.42 (53.09) [+]
RBNGS0120096 Yi individual cerebellum 10.00 (81.35)
520.64 (99.96) Full [+] 5.7 (25.26) [+]
RPKM Comparison
Human 
Macaque 
Mouse 
7.97
 
6.61
 
5.92
 
12.42
 
9.16
 
7.19
 
12.60
 
12.75
 
15.12
 
15.33
 
32.43
 
11.13
 
10.24
 
3.83
 
2.22
 
brain cerebellum heart kidney testis
Percentile Rank Comparison
Human 
Macaque 
Mouse 
77.53
 
77.94
 
67.99
 
84.01
 
82.71
 
71.25
 
88.40
 
91.42
 
85.76
 
86.31
 
95.15
 
79.94
 
74.14
 
64.73
 
56.09
 
brain cerebellum heart kidney testis
Relative RPKM Comparison
Human 
Macaque 
Mouse 
0.012
 
0.009
 
N.A
 
0.015
 
0.016
 
N.A
 
0.015
 
0.017
 
N.A
 
0.021
 
0.061
 
N.A
 
0.021
 
0.020
 
N.A
 
brain cerebellum heart kidney testis